Tim scraped his knee during a fall and it needs to be repaired. The closest skin cells begin sending out growth factors through paracrine signaling to tell all nearby skin cells to start replicating to repair the damaged area. What are the next steps once the message is sent?

The growth factors are packaged into a vesicle and secreted from a cell that acts upon all nearby cells. The cells start dividing.
The growth factors are packaged into a vesicle and secreted from a cell that acts upon target cells near and far. The cells start mitosis.
The growth factors are packaged into a vesicle and secreted from a cell that acts upon only a target nearby cell. The cell starts swelling up.
The growth factors are packaged into a vesicle and embedded into the plasma membrane where it is detected by other cells. The cells produce more proteins.