Compared with medieval art, a major theme in renaissance art was

economics.

religion.

nature.

politics.

I think the correct answer from the choices listed above is the second option. Compared with Medieval art, a major theme in Renaissance art was religion.  Humanism and the Renaissance played a direct role in sparking the Reformation, as well as in many other contemporaneous religious debates and conflicts. Hope this helps.

When you see bubbles in your pancakes

Sonata