If you made a change in the promoter sequence in the dna that inactivates the promoter, what would happen at the rna level? the mutation of the dna would be carried through to the rna sequence. the dna helicase would not be able to recognize and bind the dna, so the rna would not be made. nothing, the rna would be made as usual. the rna polymerase would not be able to recognize and bind the dna, so no rna would be made.