The metabolic fate of fatty acids is dependent on two enzymes, carnitine acyltransferase i and acetyl-coa carboxylase. carnitine acyltransferase i facilitates the transport of fatty acids to the mitochondria for β oxidation, whereas acetyl-coa carboxylase catalyzes the first reaction in the fatty acid synthesis pathway. the amp-activated protein kinase (ampk) regulates the activity of acetyl-coa carboxylase by phosphorylating a specific serine residue. mutation of this regulatory serine to alanine or aspartate would be expected to have different effects on the regulation of acetyl-coa carboxylase. select the statements that describe the expected effects of mutations of the regulatory serine.

The correct answer is the last statement.

If the regulatory serine is mutated to alanine, then acetyl-CoA carboxylase will get activated spontaneously and will produce malonyl-CoA. The increased concentrations of malonyl-CoA will obstruct the oxidation of fatty acids by preventing the entry of fatty acids into the mitochondria.

It is because the AMP-activated protein kinase phosphorylates the serine residues of acetyl-CoA carboxylase to inactivate it. If a mutation occurs in such residues, then the AMPL cannot phosphorylate acetyl-CoA carboxylase and this enzyme will get activated spontaneously.

In such a situation, there will be more than sufficient production of malonyl-CoA, which will inhibit the admittance of more fatty acid getting inside the mitochondria; this will indirectly prevent the oxidation of fatty acids.

what statement best describes the difference between the sympathetic and parasympathetic nervous systems?

the sympathetic nervous system prepares the body for intense physical activity and is often referred to as the fight-or-flight response. the parasympathetic nervous system has almost the exact opposite effect and relaxes the body and inhibits or slows many high energy functions.

there is not 1 highest source of protein, but there are many; meats, fish, poultry, seafood, cheese, eggs, yogurt and milk. the only non complete animal food that is beneficial is gelatin.

sorry if this did not , have a great day!