If mutation happen in the it could affect offspring

The only mutations that matter to large-scale evolution are those that can be passed on to offspring. These occur in reproductive cells like eggs and sperm and are called germ line mutations. A single germ line mutation can have a range of effects: No change occurs in phenotype

The only mutations that matter are the offspring that are large scale

What's the yellow wallpaper?

They are both used to view parts of the cell