Why do macromolecules need to be broken down by the body

It is is by digestion of complex molecules into simpler forms lke carbohydrates into its corresponding monosacchrides Glucose.Proteins to amino acids, Lipids to fatty acids and nuclec acids to nuclotides respectively.it is nothing but the metabolism of the complex macromolecules that we consume in the form of food.

frogs. the lower the ph the higher the acid content. frogs have the highest tolerance in this scenario.

some inherited genetic mutations can be good for the offspring, so the answer is different genetic mutations cause many forms of cancer.