Anewly synthesized protein that will be secreted by the cell follows this general pathway â

The right answer is Ribosomes from the endoplasmic reticulum ==> Golgi apparatus ==> vesicles that fuse with plasma membrane and taken out of the cell.

In the eukaryotic cell in particular, the protein must be delivered or transported from the place of synthesis to its functional compartment by a sorting and routing system.

The destination of the protein is determined by its nature thanks to the presence of specific sequence called addressing signal.

During the addressing, several molecules are used, namely: receptors specific for the targeting sequence, translocation membrane proteins and chaperone proteins.

Depending on their final destination, there are two protein addressing routes: the secretory pathway and the cytosolic pathway.