Which statement about dna replication is true?
a. eukaryotes only have one circular chromosome that unwinds at multiple locations.
b. prokaryotes only have one origin of replication to initiate replication.
c. eukaryotes can only replicate one segment of a chromosome at a time.
d. prokaryotes can only replicate their single circular chromosome in the nucleus.

The correct answer is option B, "Prokaryotes only have one origin of replication to initiate replication"

Prokaryotes have single circular molecule of DNA which has only one origin of replication per circular chromosome.  

While Eukaryotes have several origin of replication. The chromosome of Eukaryotes is linear and long due to which it has multiple replicating sites with different replication timing.  With multiple replication, the process of transcription in eukaryotes becomes fast and easy.  

Prokaryotes only have one origin of replication to initiate replication

Explanation: