What information does the first sentence convey the reader

It provides the reader with your topic and give them a central idea of your writing.

scientists have discovered that hiv does not cause aids by the virus's direct effect on the host's immune cells, but rather through the cells' lethal influence on one another. researchers from the gladstone institutes have revealed that hiv does not cause aids by the virus's

in 1859, charles darwin set out his theory of evolution by natural selection as an explanation for adaptation and speciation. he defined natural selection as the "principle by which each slight variation [of a trait], if useful, is preserved".