How do lymphatic capillaries differ from blood capillaries? illustration of lymphatic capillaries interacting with a systemic capillary bed. how do lymphatic capillaries differ from blood capillaries? illustration of lymphatic capillaries interacting with a systemic capillary bed. fluid flows in one direction in lymphatic capillaries. the walls of lymphatic capillaries are composed of endothelium. lymphatic capillaries are highly permeable. lymphatic capillaries are dead-end tubes.