All macromolecules are made mostly of the same six elements. what are
those six elements?

Carbon, hydrogen, oxygen, nitrogen, phosphorous, and sulfur.

Explanation:

Macromolecules such as carbohydrates or lipids are made of a selection of these six elements. Carbohydrates are made out of carbon, hydrogen, and oxygen--or "CHO" for short. Lipids are made out of carbon, hydrogen, and oxygen as well. Proteins are made out of carbon, hydrogen, oxygen, nitrogen, and sometimes sulfur (CHONs, the s is lowercase because sulfur does not usually appear in proteins). Nucleic acids are made out of carbon, hydrogen, oxygen, nitrogen, and phosphorous (CHONP).

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