Accurate recording of observations should be based on:

Honesty

Explanation:

Observation is essential in science. Scientists use observation to collect and record data, which enables them to construct and then test hypotheses and theories. These tools allow for more precise and accurate observations

In recording these observations, one should be completely honest and devoid of all sentimental feelings or impressions. As complete honesty leads to accurate hypothesis and theories

an active site is a region that is present on an enzyme where the reactants or the substrate molecules we can say bind and experience a chemical reaction. the substrate is basically a reactant whose concentration is changing and that is converting into a product after binding at the active site of an enzyme