Which of the following statements regarding cyclin dependent kinase inhibitors is false? a. oncogenic signaling negatively regulates cdki’s. for example, akt signaling leads to cytoplasmic sequestration of cdki’s, and myc leads to transcriptional repression of cdki genes. b. some inhibitors are specific for the cyclin d: cdk4/6 complex. these inhibitors block progression past the r point. c. the cdki’s themselves are subject to positive regulation by cell stresses such as dna damage. d. some inhibitors are able to inactivate several cyclin: cdk complexes and therefore can promote cell cycle arrest at several checkpoints. e. all of the cdki’s have similar phosphatase activities.
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Which of the following statements regarding cyclin dependent kinase inhibitors is false? a. oncogen...
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