Enzyme inhibitor disrupt normal interactions between and enzyme and

Substrate.

Explanation:

Enzyme is the bio catalyst that are used to increase the rate or speed of the biochemical reaction. Enzymes are made of proteins and are highly specific in nature.

The inhibitors may inhibit the activity of the enzyme. The inhibitors disrupt or may break the interaction between the substrate and the enzyme. They can compete with the substrate or may binds with the enzyme substrate complex and hinders the reaction.

Thus, the correct answer is substrate.

1) gene flow

- it is described as the transfer of genes from one population to another population so that frequency of gene is increased.

-a zebra migrates to join a different herd of zebras.

2) natural selection

- a mechanism of evolutionary change in which individuals with advantageous traits survive and reproduce whereas the others ( those that can not adapt) eliminate from the population.

-competition for sunlight leads to taller trees.

3) mutation

- permanent change in the nucleotide sequence of dna ( genetic material) that could have harmful or useful consequences.

-the dna of a snake changes to make its venom stronger.

4) genetic drift - it is a random phenomenon ( that occurs by chance such as fire) that results in change in the gene frequency in a small population.    

-a grassfire randomly sweeps through a population of buffalo and kills most of the animals.

explanation:

this protocol provides a detailed procedure for co-immunoprecipitation (co-ip) to identify protein–protein interactions.