Amajor group of g protein-coupled receptors contains seven transmembrane α helices. the amino end of the protein lies at the exterior of the plasma membrane. loops of amino acids connect the helices either at the exterior face or on the cytosol face of the membrane. the loop on the cytosol side between helices 5 and 6 is usually substantially longer than the others.
where would you expect to find the carboxyl end?