Which of the following events would be directly affected if a neuron had a mutation that prevented the production of voltage-gated na+ channels? which of the following events would be directly affected if a neuron had a mutation that prevented the production of voltage-gated na+ channels? graded hyperpolarization generating the resting membrane potential graded depolarization depolarization leading to action potentials

depolarization leading to action potentials

Explanation:

The voltage-gated Na+ channels are responsible for rapid depolarization phase of the action potential. Action potential generation require depolarization of neuronal membrane which is acquired by influx of sodium ions through voltage gated sodium ion channels. If the Na+ channels are blocked, there will be no influx of sodium ions to cause depolarization hence action potential will not be generated.

enzyme active site and substrate specificity

enzymes bind with chemical reactants called substrates. there may be one or more substrates for each type of enzyme, depending on the particular chemical reaction. in some reactions, a single-reactant substrate is broken down into multiple products