Why was it initially difficult for researchers to discover the existence of microtubules?
a. microtubules were too small to be seen by electron microscopy.
b. microtubules were initially thought to be the same protein fibers seen in the extracellular matrix and thus were not thought to be unique structures.
c. microtubules dissociate under the colder conditions initially used to fix tissues, and were thus disappearing during sample preparation.
d. researchers thought microtubules were appendages of the golgi apparatus. e. the marginal band obscured all visualization of the microtubules
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Why was it initially difficult for researchers to discover the existence of microtubules?
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