Atumor is actively producing both vegf and fgf, factors that stimulate angiogenesis, but no new network of blood vessels to the tumor has been established in spite of the fact that blood vessels are nearby. this observation suggests that most likely

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many other transport proteins, often called pumps, move materials against a concentration gradient. active transport drives molecules across a membrane from a region of lower concentration to a region of higher concentration. this process, shown in figure 5.1, uses transport proteins powered by chemi- cal energy.