Regulation in biological systems depends on feedback, which is an example of information flow. when diabetes destroys insulin-producing cells, what information flow is disrupted?

the body's ability to detect and control high blood sugar level,is disrupted

Explanation:in a normal functioning human system, different homeostatic processes occurs.they occur in order to keep the internal environment of the body constant.

One of such homeostatic process is the control of blood sugar level.

When food is digested and absorbed,the glucose level of the blood becomes higher,then the hormone Insulin is secreted as a negative feedback mechanism.this Insulin secreted functions to keep the glucuse level constant and it does this by converting glucose to glycogen which is stored.

The hormone glucagon acts opposite to insulin.it converts glycogen to glucose,when the glucose level in the blood is low.

During diabetes,the ability of the body to produce Insulin is reduced and as a result the glucose level of the body is constantly above normal.

For patients with diabetes,they have to be given insulin injections to regulate the level of glucose.

you are certainly talking about this picture:

a: is the label of the white square, it is showing the  replication fork, formed by helicase (d) ==> so it is the site of dna separation and replication 

b: is a new dna brand that is following directly the replication fork, so it is continuous ==> built continuously from 5' to 3

c: dna polymerase cannot replicate dna on its own, it needs the of their proteins, and one of them plays the role of a clamp which fixes  the dna with the dna template and increases  the processivity of the enzyme. ==>   stops polymerase from falling off the  template.

d: is the enzyme responsible for forming the replication fork (helicase) ==> unwinds and separates dna into two strands

e: is the delayed strand, it is built  in the opposite sense of the helicase, so dna will be built in fragments ==> built  fragments from 5' to 3 joins

and finally f: is the enzyme that builds  the new dna strand (dna polymerase) ==>   adds nucleotides to make a new dna helix.

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nucleus

would be most reasonable answer tbh