Cancer therapeutics are designed to impact the life of the replicative cell in some way. Some chemotherapy drugs target topoisomerase enzymes. Which of the following statements most accurately describes the effect of these types of anticancer drugs?

Topoisomerases are enzymes that are part of the DNA replication machinery, they have the function of temporally breaking down and rejoining the two strands of DNA, without these enzymes the processes of replication, transcription cannot be carried out. For this reason, scientists have begun to use drugs that inhibit the function of these enzymes, there are reported scientific studies where scientifics said that these drugs inhibit the topoisomerase relief reaction, thus inducing breaks in the DNA that affects cancer cells.

picture a world where computers are building made-to-order personalized robotic arms and synthetic organs, drones are circulating above mars! due to the rapid growth of technology, the future has never been more unpredictable, and it presents a huge challenge in education: we are teaching students how to work in a future that we have never been unsure of. it is widely predicted that in eight years’ time, there will be more jobs in the fields of science, mathematics, technology and engineering than in any other discipline. and, as the technology continues to develop, it will soon become clear that addressing social problems will involve more innovative thinking, and analytical and technical knowledge than ever before. undeniably, there are no subjects that encourage innovative and creative thinking, deep thought, problem solving and independence more than the stem subjects. while it is widely commented on that there is a need to reimagine the ways stem subjects are taught in schools by embracing a more interactive and innovative approach to appeal to more students, it should come as no surprise that some of the most reputable educational organizations in the world are already implementing changes to embrace stem. harvard, for example, announced in 2014 that they were increasing their computer science faculty by over 50% and has since introduced computer science as a core subject for all freshmen. the urgency of supporting stem subjects at a young age is becoming more relevant than ever, as adopting a keen interest in the curricula needs to happen early. however, beyond the age issue is one of gender.

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