Humans vary in their ability to taste the bitter chemical compound phenylthiocarbamide (PTC). The aividuals from an isolated population, In the sample, 780 individuals were able to taste PTC and taster phenotype is dominant to the nontaster phenotype, Researchers tested the PTC taster phenotype of indiciduals from an isolated population. In the sample, 708 individuals were able to taste PTC and 70 individuals were not able to taste PTC. Assuming the population is in Hardy-Weinberg equilibrium, what is the frequency of the non-taster allele? A. 0.08 B. 0.41
C. 0.29 D. 0.71

C. 0.29

Explanation:

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The Hardy-Weinberg equilibrium establishes that the frequencies of the different genotypes that are formed during mating depend solely on the allelic frequencies of the population. Considering an autosomal locus, when the population is infinitely large and is not subject to any evolutionary force, both allelic and genotypic frequencies will remain constant from generation to generation, being able to predict their values for future generations.

When the population is in Hardy-Weinberg equilibrium, genotypic frequencies are given following the binomial model:

p²= f(A₁A₁)   2pq= f(A₁A₂)   q²= f(A₂A₂)

and

p²= P   2pq= H   q²= Q

Considering the autosomal locus with two alleles A₁ A₂, where A₁ shows complete dominance over A₂(resesive)

P: f(A₁A₁), H: f(A₁A₂) and Q: f(A₂A₂) represent the genotipic frequencies and P+H+Q=1

and p: f(A₁)= P and q: f(A₂) represent the allelic frequencies and p + q= 1

The given information is:

Phenotipe: "Ability to taste PTC" is dominant to the Phenotipe: "Incapable of tasting PTC"

This means that both homozygous-dominant and heterozygous individuals present the phenotipe "Ability to taste PTC" and only homozygous-resesive individuals present the phenotipe "Incapable of tasting PTC"

Sample size: 780

708 individuals were able to taste PTC ⇒ These represent the homozygous-dominant and heterozygous individuals of the population.

70 individuals were incapable of tasting PTC ⇒ These represent the homozygous-resesive individuals of the population.

The frequency of the non taster allele is:

The correct option is C

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