Genetically modified organisms include microbes used in biotechnology that possess enzymes promoting antibiotic resistance. This could be a problem given the rise of antibiotic-resistant organisms. However, these engineered microorganisms do not pose a risk to public health. What do you think prevents them from spreading antibiotic resistance to pathogens outside the laboratory?
These microbes have been designed so that conditions outside the laboratory would be unfavorable to their survival.

Inability to survive in wild environmental condition

Explanation:

Genetically modified organisms that are developed under a certain environmental condition are not able to survive in wild natural environmental conditions. Due to this, the antibiotic resistant GMOs will not be able to thrive outside the laboratory otherwise they could have easily affected other organism as they are resistant to their immune systems. The wild conditions outside the laboratory will not provide suitable mating conditions as well for genetic recombination and gene transfer