Biology, 25.02.2020 18:26 krutikov686
[methyl-14C]pyruvate was administered to isolated guinea pig liver cells in the presence of sufficient malonate to completely block the action of succinate dehydrogenase. After a time, isocitrate is isolated and found to contain radiolabeled carbon at both the —CH2— and the —CHOH— carbons, instead of just at
the —CH2— carbon. Explain how the —CHOH— got radiolabeled.
Answers: 1
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