Tests reveal that Mrs. Rogers's mitral valve does NOT close properly, allowing a backflow of blood with each heart contraction. The medical word to describe this valve problem is .

Tests reveal that Mrs. Rogers's mitral valve does NOT close properly, allowing a back-flow of blood with each heart contraction. The medical word to describe this valve problem is mitral valve regurgutation. it is caused due to the non-closure of mitral valve  in proper tight manner which leads to the back flow of blood continuously with every contraction.

Explanation:

It is a pathological (medical) condition when the heart's mitral valve doesn't close properly (tightly), allowing the blood to flow backward in the heart.

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enzyme active site and substrate specificity

enzymes bind with chemical reactants called substrates. there may be one or more substrates for each type of enzyme, depending on the particular chemical reaction. in some reactions, a single-reactant substrate is broken down into multiple products