Marijuana has been known to produce memory effects in long-time users. This result is most likely due to the altering of a large percentage of receptors in the of the brain.

Canabinoid

Hippocampus

Explanation:

Tetrahydrocannabinol (THC) is a very potent psychoactive drug. Once in the bloodstream, it reaches the brain in seconds. When marijuana is inhaled, it spread round the body releasing THC. THC move to the brain and begin it's work immediately.

The brain has group of cannabinoid receptors and these receptors are activated by a neurotransmitter known as anandamide. Cannabinoid receptors can affect short-term memory, thinking, coordination and problem solving.

Anandamide is a cannabinoid made in the body. THC mimics the action of anandamide by binding to cannabinoid receptors which activate neurons which causes adverse effects of the mind and body.

High concentration of the cannabinoid receptors are found in the Hippocampus which is responsible for short memory. Once the THC binds the cannabinoid receptors in the Hippocampus, it affects the memory and make it impossible to recall recent events.

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