In positive control of several sugar metabolism-related operons, the cAMP receptor protein (CRP) binds to DNA to stimulate transcription. Which of the following environmental conditions causes an increase in CRP activity in stimulating transcriptionCorrect a decrease in glucose and an increase in cAMP

CRP (cAMP receptor protein) is a protein found in bacteria. It is a regulatory protein.

Explanation:

CRP binds to cAMP which brings the conformational change which leads to the binding of CRP to specific sites on DNA promoter. This activates the transcription through interaction with RNA polymerase. Decrease in glucose and increase in cAMP causes an increase in CRP activity. cAMP is low when glucose behaves as a carbon source. This is due to inhibition of adenylate cyclase enzyme (cAMP producing enzyme). So, a decrease in glucose level will increase cAPM level.

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