The TCbusiness toxin binds to the C-terminus domain of RNA pol II in eukaryotes and renders it completely non-functional. Obviously this would be disastrous; tell me ONE thing that would be affected in a cell poisoned with TCbusiness and briefly explain your answer. (3 sentences max)

Explanation:

RNA polymerase II is the enzyme that is responsible for the transcription of the DNA into the mRNA molecule in the eukaryotes.

The polymerase activity of RNA polymerase II is due to a specific sequence of nucleotides present at the C terminal end of protein and it is this C terminal domain that the RNA polymerase enzyme is involved in transcription, splicing, and capping.

If a toxin, in case binds to the C terminal of this domain then all of these functions will be disturbed and the enzyme will not be able to perform its function and the cell would be dead.

a covalent bond, specfically triple bond