Biology, 16.04.2020 21:40 Tyrant4life
The information in pedigrees that is useful for mapping disease genes is sometimes limited. This pedigree shows segregation of neurofibromatosis, which is a fully-penetrant, autosomal dominant condition, and a single nucleotide polymorphism, SNP1, which has alleles G or T. Why is the cross in generation I not useful for determining the degree of linkage between the disease-causing gene NF and SNP1?
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The information in pedigrees that is useful for mapping disease genes is sometimes limited. This ped...
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