Explain how the properties of water that result from its polarity and hydrogen bonding affect its biological function. Describe the composition of macromolecules required by living organisms. Describe the properties of the monomers and the type of bonds that connect the monomers in biological macromolecules. Explain how a change in the subunits of a polymer may lead to changes in structure or function of the macromolecule. Describe the structural similarities and differences between DNA and RNA.