What does it mean when we say a gene is "turned off"? What does it mean when we say a gene is "turned off"? The gene is now activated. The gene cannot be transcribed and translated into a protein. The gene has a mutation. The gene is no longer working properly.

The gene cannot be transcribed and translated into a protein.

Explanation:

Turning off a gene means the gene cannot be transcribed and translated into a protein.

Turning off of genes is a form of gene regulation, a process that controls which genes are expressed or not expressed in a cell.

The expression of genes requires that they are first transcribed from DNA to mRNA in the nucleus and then moved to cytoplasm where they are translated into proteins by the ribosome.

Hence, a gene that will not be expressed has to be stopped from being transcribed amd translated by being turned off by the gene regulation process of the cell.

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