Club foot is one of the most common congenital skeletal abnormalities, with a worldwide incidence of about 1 in 1000 births. Both genetic and nongenetic factors are thought to be responsible for club foot. C. A. Gurnett et al. (2008. American Journal of Human Genetics 83:616–622) identified a family in which club foot was inherited as an autosomal dominant trait with reduced penetrance. They discovered a mutation in the PITXI gene that caused club foot in this family. Through DNA testing, they determined that 11 people in the family carried the PITXI mutation, but only 8 of these people had club foot. What is the penetrance of PITXI mutation in this family? Please round to two decimal places (e. g. 0.01).

Penetrance might be characterized as the part of the predetermined genotypes populace that shows the normal phenotype.  

Here, total number of genotypes (PITXI transformation observed) = 11  

Genuine influenced phenotypes = 8  

Penetrance =  (Watched number of club foot occasions) / (all out number of people with PITXI transformation)  

 Penetrance = 8/11

Penetrance = 0.72

there are mainly three domains in biological classification namely; archaea, bacteria, and eukarya.

archaea includes all the prokaryotic cells which are characterized by their lipid membranes. they have branched hydrocarbon which is attached to glycerol through an ether linkage.

bacteria includes all the prokaryotic cells, the cell membrane of which are made up of the unbranched fatty acid chain. in addition, they are attached to glycerol through an ester bond.

eukarya includes all the eukaryotic cells, that is, the cells contain a nucleus and other membrane-bound cell organelles.

they can be autotrophic as well as heterotrophic, unicellular as well as multicellular

they include kingdoms like protista, plantae, animalia, fungi et cetera.

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explanation:

lipid

explanation: