You have cloned a gene for a human erythrocyte protein which you suspect is a membrane protein. From the nucleotide sequence of the gene, you know the amino acid sequence.

a. From this sequence alone, how would you evaluate the possibility that the protein is an integral protein?

b. Suppose the protein proves to be an integral protein, either type I or type II; suggest biochemical or chemical experiments that might allow you to determine which type it is.