A number of experiments have demonstrated that areas of the genome that are relatively inert transcriptionally are resistant to DNase I digestion; however, those areas that are transcriptionally active are DNase I sensitive. Describe how DNase I resistance or sensitivity might indicate transcriptional activitA) When DNA is transcriptionally active, it is in a more condensed state and as such, more open to DNase digestion. B) When DNA is transcriptionally active, it is in a less condensed state and as such, more open to DNase digestion.