What is one way that early scientific practice differed from modern scientific practice?

early hypotheses were not based on observations.
early hypotheses were not tested by experimentation.
early hypotheses were formed from scientific questions.
early hypotheses were influenced by creative thinking

The correct answer is this: EARLY HYPOTHESES WERE NOT TESTED BY EXPERIMENTATION.
An hypothesis refers to a proposed explanation for an observed phenomenon. Formulation of an hypothesis is usually the first step in the process of scientific investigation. Both early and modern scientific practices make use of hypotheses but the early scientific hypotheses were not tested by experimentation. In the scientific world today, for an hypothesis to be acceptable to other scientists and for it to become a theory, it must be tested several times and the results obtained must be constant.

"Early hypotheses were not tested by experimentation" is the one way among the choices given in the question that early scientific practice differed from modern scientific practice. The correct option among all the options that are given in the question is the second option. I hope the answer helps you.