Which of the following statements about enzyme inhibition is true?

a. Most noncompetitive inhibitors bind to several different sites on an enzyme.
b. Enzymes become less efficient as temperatures drop because they begin to denature.
c. Most human enzymes have an optimum temperature below normal body temperature.
d. Non-competitive inhibitors bind to a site other than the active site.

The correct option is d: "Non-competitive inhibitors bind to a site other than the active site."

Explanation:

The active site of the enzyme is where the substrate binds. When this binding has taken place, the enzyme is able to convert the substrate into products. If a competitor binds to the active site due to its complementary structure, the substrate will be unable to bind and therefore, no products will be formed - this type of molecule is referred to as a competitive inhibitor. A non-competitive inhibitor is called as such because it is not competing to bind to the active site of the enzyme.

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