Many intracellular signaling proteins act as switches that toggle from an inactive to an active state. Once activated, these signaling proteins can stimulate—or in some cases inhibit—other proteins in the signaling pathway. An interaction that results in stimulation is often depicted by an arrowhead (→), whereas inhibition is indicated by a crossbar (—I). In which of the hypothetical signaling pathways outlined below would activation of the receptor lead to an increase in gene expression?

Hello. You forgot to enter the answer options. The answer options are in the figure attached below:

the option D is the right answer.

Explanation:

Option D shows a pathway where activation of the receptor would lead to an increase in gene expression. This is because in this option we can see that the transcription regulator is decreasing gene expression, but there is a receptor that is activated and that has the ability to inhibit the pathway, allowing the selected gene to be expressed efficiently. This is because the pathway shows two inhibitory steps, when this happens an activation is performed.