Which of the following genetic changes cannot convert a proto-oncogene into an oncogene? A mutation in the promoter of the proto-oncogene, causing the normal protein to be transcribed and translated at an abnormally high level. A mutation that introduces a stop codon immediately after the codon for the initiator methionine. An amplification of the number of copies of the proto-oncogene, causing overproduction of the normal protein. A mutation within the coding sequence that makes the protein hyperactive. A genetic rearrangement where proto-oncogene coding sequence becomes fused with the promoter of a highly active promoter.