The graph below shows drug levels in the blood and in a target organ through time, while taking Pill Type C in the Gizmo. The dosage schedule is one pill every two hours. What will eventually happen if the patient continues to take the pill on the same dosage schedule?

Correct B. The drug level in the target organ will level off and reach equilibrium.

Explanation:

As long as the dosage schedule is maintained, the drug level in the target organ and blood will stabilize. The reason for this is that as the concentration of drug increases in the organ and blood, the amount of drug removed by the kidneys increases as well, as each cubic centimeter of liquid removed from the blood by the kidneys contains a greater amount of drug. Eventually, the amount of drug removed in the time period between pills is equal to the amount that is added with each pill. As the graph below shows, the maximum organ drug level in this example is about 192 mcg/cc.

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