The map shows the allele frequency of sickled hemoglobin (HbS) and malaria endemicity in Africa. Which statement best explains the relationship between HbS allele frequency and malaria endemicity in Africa?
When an area is malaria free, the HbS allele frequency is between 0 and 2.02.
When an area is holoendemic, the HbS allele frequency is between 0.52 and 4.04.
When an area is malaria free, the HbS allele frequency is between 12.64 and 18.18.
When an area is holoendemic, the HbS allele frequency is between 0 and 0.51.

20 point pls brianliest 1. what does a red shift mean? blue shift? 2. describe the big bang theory. according to this theory, how old is the universe? 3. scientists believe the universe is expanding. what is the evidence that supports this? 4. describe a nebula. 5. describe the 3 types of galaxies. what is a barred spiral galaxy? 6. what is a light year? how far is alpha centauri from earth? 7. describe the universal law of gravitation. be sure to include gravitational force between two objects. 8. describe the planets’ orbits around the sun. 9. what is the asteroid belt? where is it located? 10. describe rotation and revolution of earth. what determines an earth day and year? 11. how do galaxies exist? 12. compare and contrast the inner and outer planets. 13. what causes the seasons?