A medical test indicates that a patient has a defective protein. This condition is most likely due to a change in the directions coded in the:

number of phosphate molecules

sequence of subunits in DNA

number of nitrogen bases

sequence of sugar molecules

number of nitrogen bases

Explanation:

The correct answer would be the number of nitrogen bases.

A defective protein is usually caused by mutation, which is defined a change in the DNA sequence of an organism.

Mutation can occur in a variety of ways including:

1. Deletion of nucleotide base sequence in the DNA

2. Addition (insertion) of nucleotide base sequence in the DNA

3. Duplication of nucleotide sequence in the DNA

A change in number of phosphate molecules, sequence of subunits DNA and sequence of sugar molecules if possible in nature, do not lead to mutation if the change does not affect the sequence of DNA.

Hence, the correct option is number of nitrogen bases.

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