MINI Sickle-cell disease is a group of genetic disorders that affect hemoglobin, which is the
protein in red blood cells that binds to oxygen. The change to the hemoglobin molecule
causes the red blood cells to have a crescent or sickled shape. The diagram on this
question shows a fragment of the DNA sequence for hemoglobin in a person without
sickle-cell disease and in a person with the disease.
Why
INI!!
HOC
22
11111
What amino acid pair reflects the mutation leading to sickled red blood cells?
Q Zoom
A
Valine to Histidine
B
Glutamic acid to Valine
с
CTC and CTC
D
CAC and GGA
E
Glutamic acid to Glutamic acid