Which of the following is a description consistent with acute lymphocytic leukemia (ALL)? There are defects in the ras oncogene, p53 tumor suppressor gene, and INK4A, the gene encoding a cell-cycle regulatory protein. The bone marrow and peripheral blood are characterized by leukocytosis and a predominance of blast cells. As the immature blasts increase, they replace normal myelocytic cells, megakaryocytes, and erythrocytes. There is failure of B cells to mature into plasma cells that synthesize immunoglobulins. The translocation of genetic material from genes 9 and 22 create an abnormal, fused gene identified as BCR-ABL
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Which of the following is a description consistent with acute lymphocytic leukemia (ALL)? There are...
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