What is believed to be the main reason for the poor cloning efficiency of the nuclear implantation method?

The options are not given, here are the options.

A) the lack of an effective method to induce division of the product of the somatic cell fusion product

B) the difficulty in extracting nuclei from somatic cells

C) the lack of an efficient method for injecting the somatic cell nucleus into the egg cell

D) variations in the completeness of epigenetic programming of the somatic cell nucleus

The correct option is

D) variations in the completeness of epigenetic programming of the somatic cell nucleus

Explanation:

Nuclear transplantation method is the method in which the nucleus from a donor cell is removed and inserted in the target cell in which also it's nucleus has been removed or enucleated. The nuclear transplantations has slowed

embryologists to interfere the development of an organism and to study nucleus to direct development. It has been used for the cloning of several species.

Nuclear transplantation has failed in cloning because variations in the completeness of epigenetic programming of the somatic cell nucleus.

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