Which is the pair of the enzyme activities most significantly affected by glucagon- and insulin-dependent phosphorylation and dephosphorylation of 6-phosphofructo-2-kinase/fructose-2 ,6-bisphosphatase (PFKFB)? a. hexokinas glucose-6-phosphatase
b. phosphofructokinase Fructose-1,6-bisphosphatase
c. pyruvate kinase pyruvate carboxylase
d. glycogen synthase glycogen phosphorylase
e. None of these

b. Phosphofructokinase;  Fructose-1,6-bisphosphatase

Explanation:

Glucagon is a hormone which functions to initiate gluconeogenesis whwreas insulin functions to initiate glycolysis.

Fructose-2,6-bisphosphate (F26BP) is an allosteric regulator of the glycolytic and gluconeogenic enzymes phosphofructokinase-1 (PFK-1) and fructose-1,6-bisphosphatase (FBPase-1).

It stimulates glycolysis and inhibits gluconeogenesis by binding to its allosteric site on phosphofructokinase-1 reducing its affinity for the allosteric inhibitors ATP and citrate .

It is formed by phosphorylation of fructose-6-phosphate catalyzed by  phosphofructokinase-2 and is broken down by fructose-2,6-bisphosphatase which are two separate enzymatic activities of a single, bifunctional protein (PFK-2/FBPase-2).

Phosphorylation of PFK-2/FBPase-2 due to glucagon release enhances its FBPase-2 activity thereby stimulating gluconeogenesis and inhibiting glycolysis.

Dephosphsorylation of PFK-2/FBPase-2 due to insulin release enhances its PFK-2 activity, thereby stimulating glycolysis and inhibiting gluconeogenesis.

it enhances antibody production by t cells of the adaptive immune system.

hope i'm right

explanation:

when you breathe in, or inhale, your diaphragm contracts (tightens) and moves downward. this increases the space in your chest cavity, into which your lungs expand. the intercostal muscles between your ribs also enlarge the chest cavity. they contract to pull your rib cage both upward and outward when you inhale.