Which enzyme does lovastatin inhibit? (Hint: Pay special attention to the highlighted portion of the molecule.)

Lovastatin, which demonstrates a cholesterol-lowering effect by the inhibition of HMG-CoA reductase, may also have an anti-methanogenesis effect through direct inhibition of enzymes in the archaeal methanogenesis pathway. We conducted protein-ligand docking experiments to evaluate this possibility.

Explanation:

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