Li-Fraumeni syndrome (LFS1) is a rare hereditary disorder that leads to a predisposition to cancer. This hereditary disorder is linked to mutations in the tumor suppressor gene encoding the transcription factor p53. p53 acts at the G1 checkpoint. If damaged DNA is detected, p53 halts the cell cycle. As p53 levels rise, the production of p21 is triggered. p21 enforces the halt in the cell cycle. A variant of Li-Fraumeni, called LFS2, is thought to occur due to a mutation of the CHK2 gene, which is also a tumor suppressor gene. CHK2 regulates the action of p53. Which of the following cascades is most likely to occur in a normal cell that does not contain the LFS mutation?

Hurry i need your (100 points) 1) what are the responsibilities of the region of the brain highlighted below? (picture located below) the highlighted portion is at the rear base of the brain, behind the brain stem. regulating homeostasis, hunger and eating, thirst and drinking, and many other functions of basic survival. coordinating movement and balance by using information from sensory nerves, including hand-eye coordination. controlling voluntary body movements, processing information from sense organs, thoughts, and learning abilities. regulating important involuntary bodily functions such as blood pressure, heart rate, breathing, and swallowing. 2)which of the following systems or structures is correctly paired with its function? neurons - brain cells that control thoughts, calculations, and memory cerebral cortex - portion of the brain that controls involuntary body movement peripheral nervous system - carries impulses to and from the central nervous system central nervous system - carries information from the nerves to the muscles and glands