Sickle cell anemia is a genetic disorder caused by recessive alleles that can cause hemoglobin molecules to stick together. The gene for normal hemoglobin is dominant. If a hybrid man and a heterozygous woman have
a child, what is the chance that their child will have sickle cell anemia?
100%
25%
50%
0%

GREETINGS!

The sickle cell anemia allele is autosomal, meaning it can be found on one of the other 22 pairs of chromosomes, but not on the X or Y chromosome.

Hybrid trait is a heterozygous trait i.e. pair of dominant and recessive allele so that means they both man and woman are carriers, so when both the parents CARRIERS there are 25 % for children to be affected by this disorder

WHAT ARE ALL SCENERIOS FOR SICKLE CELL ANEMIA?

Scenario 1. Neither parent has the recessive sickle cell allele. None of their children will have sickle cell anemia or be carriers of the recessive allele.

Scenario 2. One parent is a carrier while the other isn’t. None of their children will have sickle cell anemia. But there’s a 50 percent chance that children will be carriers.

Scenario 3. Both parents are carriers. There’s a 25 percent chance that their children will receive two recessive alleles, causing sickle cell anemia. There’s also a 50 percent chance that they will be a carrier. Lastly, there’s also a 25 percent chance that their children won’t carry the allele at all.

Scenario 4. One parent isn’t a carrier, but the other has sickle cell anemia. None of their children will have sickle cell anemia, but they’ll all be carriers.

Scenario 5. One parent is a carrier and the other has sickle cell anemia. There’s a 50 percent chance that children will have sickle cell anemia and a 50 percent chance they’ll be carriers.

Scenario 6. Both parents have sickle cell anemia. All of their children will have sickle cell anemia.

I HAVE MENTIONED ALL THE SCENERIOS POSSIBLE IN SICKLE CELL

HOPE THIS HELPS YOU!

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