Which treatment is commonly used to manage stress and anxiety that are related to a disorder? O physical therapy
O insulin injections
meditation
O manipulation

I would say Physical therapy it sounds the most reasonable

Explanation:

an active site is a region that is present on an enzyme where the reactants or the substrate molecules we can say bind and experience a chemical reaction. the substrate is basically a reactant whose concentration is changing and that is converting into a product after binding at the active site of an enzyme