Explain what effectors can allosterically regulate each enzyme, the cellular conditions that lead to each effector being produced, and the metabolic benefit of the regulation. a. Pyruvate carboxylase
b. Fructose 1,6-phosphatase

Explain why the enzyme glucose-6-phosphatase was not included in the previous question, despite being a point of regulation for gluconeogenesis.

Imagine a self-reactive t cell that has not undergone clonal deletion in the thymus (that is to say, it has escaped central tolerance). if it encounters self antigen in the absence of an infection or inflammation, what will happen to this self-reactive t cell? (select two answers) (a) the t cell undergoes clonal expansion. (b) the t cell gains effector functions. (c) the t cell undergoes apoptosis. (d) the t cell becomes activated. (e) the t cell becomes anergic.