What is the open area where an enzyme attaches called?

The open area where the substrate is attached to an enzyme is called the active site.

Explanation:

The active site of an enzyme corresponds to the place where the tertiary structure of this molecule leaves a free space to couple the substrate and be able to catalyze a chemical reaction.

Since the enzyme-substrate complex functions as a key lock system, the active site has a three-dimensional configuration that only admits certain molecules as substrate, which determines its specificity.

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